Introduction Amenorrhea is a medical term for the absence of menstrual bleeding. Women who have missed at least three menstrual periods in a row have amenorrhea, as do girls who haven't begun menstruation...
Introduction Adrenarche is a lot like puberty; it’s characterized by changes in the body as the child enters teen years. Premature adrenarche is when these changes begin early, before age 8 for girls and...
https://www.magicfoundation.org/ The MAGIC Foundation is a nonprofit, national organization created to provide support and educational services for the families of children who have a wide variety of ch...
http://www.saizenus.com/ Saizen® is used for growth hormone therapy to replace the hormone that the body fails to produce on its own. It works to stimulate skeletal growth, increase the number and size...
Introduction Vitamin D is labeled as the "sunshine vitamin," as it is produced in the skin on sun exposure. Vitamin D is required to maintain serum calcium concentration within the normal physiologic rang...
Introduction Turner syndrome (TS), also known as congenital ovarian hypoplasia syndrome, occurs when the X chromosome is partially or completely missing in females. Its main clinical manifestations includ...
Introduction Small for gestational age (SGA) is a term used to describe babies who are smaller than usual for the number of weeks of pregnancy. These babies have birth weight below the 10th percentile. Th...
Introduction Delayed puberty is defined clinically by the absence or incomplete development of secondary sexual characteristics bounded by an age at which 95 percent of children of that sex and culture ha...
Introduction Precocious puberty refers to the appearance of physical and hormonal signs of pubertal development at an earlier age than is considered normal. For many years, puberty was considered precocio...
Introduction Women with polycystic ovarian syndrome (PCOS) have abnormalities in the metabolism of androgens and estrogen and in the control of androgen production. PCOS can result from abnormal function...
Introduction Klinefelter syndrome (KS) is the result of 2 or more X chromosomes in a phenotypic male. The clinical phenotype of KS was first described in males with tall stature, small testes, gynecomasti...
Summary Hypopituitarism is a dysfunction of the pituitary gland, during which it fails to produce a sufficient amount of one or more hormones. The pituitary gland is part of the endocrine system and is re...
Introduction Hashimoto's disease or Hashimoto’s thyroiditis or chronic lymphocytic thyroiditis is an autoimmune disease where the body's own antibodies attack the cells of the thyroid. Hashimoto's thyroid...
Introduction Gynecomastia is a benign enlargement of the male breast (usually bilateral but sometimes unilateral) resulting from a proliferation of the glandular component of the breast. It is defined cli...
Introduction Growth hormone deficiency (GHD) is a medical condition due to not enough growth hormone (GH). Generally, the most noticeable symptom is a short height. In newborns there may be low blood suga...
Introduction Non-classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency (NCAH) is a milder and later onset form of a genetic condition known as congenital adrenal hyperplasia. Some people...
Introduction Adrenal insufficiency is caused by failure of the adrenal glands to produce sufficient (or any) amounts of cortisol and aldosterone. Prolonged lack of cortisol leads to severe fatigue, chroni...
Summary Congenital Adrenal Hyperplasia (CAH) is a term combining several rare, genetic autosomal recessive disorders that are inherited by children when both of the parents are carriers of a mutated gene....
Introduction Hyperthyroidism is a set of disorders that involve excess synthesis and secretion of thyroid hormones by the thyroid gland, which leads to the hypermetabolic condition of thyrotoxicosis. Hyp...
Introduction Idiopathic short stature (ISS) refers to extreme short stature that does not have a diagnostic explanation (idiopathic designates a condition that is unexplained or not understood) after an o...
The objective is to examine the metabolic alterations secondary to growth hormone therapy (GHT) in growth hormone deficient and non-growth hormone deficient children....
The objective of this study is to evaluate an artificial pancreas system with no exercise or meal announcements using the DiAs platform. (Mount Sinai is an additional site to an existing cohort of 3 NIH fu...